Complete structural assignment of serratol, a cembrane-type diterpene from <em>Boswellia serrata</em>, and evaluation of its antiprotozoal activity (Publications)
From the dichloromethane extract obtained from the gum resin of Boswellia serrata Roxb. (Burseraceae), a well-known medicinal plant resin ("Indian Olibanum"), the cembrane-type diterpene serratol was
Screening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of Croconazole... (Publications)
An Alamar Blue-based growth inhibition assay has been adapted for the thermosensitive and slow growing pathogen Mycobacterium ulcerans (M. ulcerans). The standardized test procedure enables medium-thr
Systems parasitology: effects of <em>Fasciola hepatica</em> on the neurochemical profile in the rat brain (Publications)
We characterize the integrated response of a rat host to the liver fluke Fasciola hepatica using a combination of (1)H nuclear magnetic resonance spectroscopic profiles (liver, kidney, intestine, brai
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones (Publications)
The anti-trypanosomal activity of six sesquiterpene lactones (helenalin, mexicanin I, 11alpha,13-dihydrohelenalin acetate, chamissonolide, ivalin and isoalantolactone) against the African Trypanosoma
Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzania infants: a randomised, placebo-controlled trial (Publications)
BACKGROUND: Clinical malaria and severe anaemia are major causes of paediatric hospital admission and death in many malaria-endemic settings. In the absence of an effective and affordable vaccine, con
Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study (Publications)
BACKGROUND: Growing up on a farm and an anthroposophic lifestyle are associated with a lower prevalence of allergic diseases in childhood. This might be related to increased inhalatory exposure to mic
Rare human infection with the trematode <em>Echinochasmus japonicus</em> in Lao PDR (Publications)
Food-borne trematodiases are often neglected although millions of people are affected and these zoonotic diseases are emerging in some parts of the world. Humans acquire an infection through consumpti
A point mutation in codon 76 of <em>pfcrt </em>of <em>P. falciparum </em>is positively selected for by chloroquine treatment in Tanzania (Publications)
This study was undertaken to validate the relevance of Chloroquine (CQ) resistance markers pfcrt(76) and pfmdr1(86) in an endemic area in Tanzania. After treatment with CQ, recrudescence was distingui
New world cutaneous leishmaniasis in travellers (Publications)
As travel to Latin America has become increasingly common, cutaneous leishmaniasis is increasingly seen among returning travellers--eg, the number of observed cases has doubled in the Netherlands and
