Strategies for understanding and reducing the <em>Plasmodium vivax</em> and <em>Plasmodium ovale</em> hypnozoite reservoir in Papua New Guinean... (Publications)
BACKGROUND: The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study a
Improving health outcomes through concurrent HIV program scale-up and health system development in Rwanda: 20 years of experience (Publications)
The 1994 genocide against the Tutsi destroyed the health system in Rwanda. It is impressive that a small country like Rwanda has advanced its health system to the point of now offering near universal
Innovative tools and OpenHDS for health and demographic surveillance on Rusinga Island, Kenya (Publications)
BACKGROUND: Health in low and middle income countries is on one hand characterized by a high burden associated with preventable communicable diseases and on the other hand considered to be under-docum
Bifidobacteria strains isolated from stools of iron deficient infants can efficiently sequester iron (Publications)
BACKGROUND: Bifidobacteria is one of the major gut commensal groups found in infants. Their colonization is commonly associated with beneficial effects to the host through mechanisms like niche occupa
Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis (Publications)
BACKGROUND: There has been progress towards malaria elimination in the last decade. In response, WHO launched the Global Technical Strategy (GTS), in which vector surveillance and control play importa
Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea (Publications)
BACKGROUND: The major malaria vectors of Papua New Guinea exhibit heterogeneities in distribution, biting behaviour and malaria infection levels. Long-lasting, insecticide-treated nets (LLINs), distri
The time-course of protection of the RTS,S vaccine against malaria infections and clinical disease (Publications)
BACKGROUND: Recent publications have reported follow-up of the RTS,S/AS01 malaria vaccine candidate Phase III trials at 11 African sites for 32 months (or longer). This includes site- and time-specifi
A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic... (Publications)
BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, the number of affected individuals is rising, with significant impacts for healthcare systems. Current symptomatic treatments
Environmental and behavioural determinants of leptospirosis transmission: a systematic review (Publications)
BACKGROUND: Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmiss
Childhood illness prevalence and health seeking behavior patterns in rural Tanzania (Publications)
INTRODUCTION: This paper identifies factors influencing differences in the prevalence of diarrhea, fever and acute respiratory infection (ARI), and health seeking behavior among caregivers of children
