FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug... (Publications)
BACKGROUND: A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider imple
Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin (Publications)
BACKGROUND: Buruli ulcer caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic necrotising skin ulcers. The pathogenesis is associated with the cytocidal and i
Impact of promoting longer-lasting insecticide treatment of bed nets upon malaria transmission in a rural Tanzanian setting with pre-existing high... (Publications)
BACKGROUND: The communities of Namawala and Idete villages in southern Tanzania experienced extremely high malaria transmission in the 1990s. By 2001-03, following high usage rates (75% of all age gro
Validation of activity questionnaires in patients with cystic fibrosis by accelerometry and cycle ergometry (Publications)
BACKGROUND: The objective of this study was to validate physical activity questionnaires for cystic fibrosis (CF) against accelerometry and cycle ergometry. METHODS: 41 patients with CF (12-42 years)
Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to <em>Plasmodium falciparum</em> and <em>P. vivax</em>: a... (Publications)
BACKGROUND: Intermittent preventive treatment in infants (IPTi) has been shown in randomized trials to reduce malaria-related morbidity in African infants living in areas of high Plasmodium falciparum
Interactions and potential implications of <em>Plasmodium falciparum</em>-hookworm coinfection in different age groups in south-central Côte... (Publications)
BACKGROUND: Given the widespread distribution of Plasmodium and helminth infections, and similarities of ecological requirements for disease transmission, coinfection is a common phenomenon in sub-Sah
The acceptability of intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in... (Publications)
BACKGROUND: Intermittent preventive treatment of malaria in infants (IPTi) reduces the incidence of clinical malaria. However, before making decisions about implementation, it is essential to ensure t
<em>Plasmodium falciparum</em> msp1, msp2 and glurp allele frequency and diversity in Sub-Saharan Africa (Publications)
BACKGROUND: The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order to capture late failures. Ho
