Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with... (Publications)
BACKGROUND: Combination treatments, preferably containing an artemisinin derivative, are recommended to improve efficacy and prevent Plasmodium falciparum drug resistance. Our aim was to show non-infe
The AGC kinase, PINOID, blocks interactive ABCB/PIN auxin transport (Publications)
Plant growth and development is determined by intracellular and intercellular auxin gradients that are controlled at first hand by auxin efflux catalysts of the ABCB/PGP and PIN families. ABCB transpo
Trisubstituted pyrimidines as efficacious and fast-acting antimalarials (Publications)
In this paper we describe the optimization of a phenotypic hit against Plasmodium falciparum, based on a trisubstituted pyrimidine scaffold. This led to compounds with good pharmacokinetics and oral a
Earthquake awareness and perception of risk among the residents of Istanbul (Publications)
Awareness and perception of risk are among the most crucial steps in the process of taking precautions at individual level for various hazards. In this study, we investigated the factors affecting bet
Antimalarial spiro-bridged 1,2-dioxolanes via intramolecular addition of peroxycarbenium ions to C-C double bonds (Publications)
Several 1,2-dioxolanes embedded in a rigid spiro-bridge framework fused with a built-in UV chromophore were synthesized through intramolecular [3+2] addition of in situ generated peroxycarbenium ions
