Physical fitness and nutritional anthropometric status of children from disadvantaged communities in the Nelson Mandela Bay region (Publications)
Background: Information about the relationships between physical fitness, body composition and nutrition has increased in recent years; however, little is known about physical fitness and the coexiste
Functional limb anatomy in a refugee species: the endangered Patagonian huemul deer (<em>Hippocamelus bisulcus</em>) (Publications)
Early naturalists already considered huemul rare, refuged and a stocky, short-legged mountain deer, 163 years before declared endangered (1972). Anatomically, huemul do not overlap with rock-climbers
Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a... (Publications)
BACKGROUND: In sub-Saharan Africa, home-based HIV testing is validated and accepted, but coverage is low because household members are often absent during home-based testing campaigns. We aimed to mea
Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of <em>Plasmodium falciparum</em> malaria (Publications)
BACKGROUND: Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to b
Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired... (Publications)
INTRODUCTION: Community-acquired pneumonia (CAP) causes around 10 hospitalisations per 1000 child-years, each associated with an average 13 non-routine days experienced and more than 4 parent workdays
Insights gained from conductinga randomised controlled trial onIvermectin-albendazole against <em>Trichuris trichiura </em>in Côte d’Ivoire, Lao PDR... (Publications)
There is only limited scientific literature on trial methodology, trial procedures and mit-igation strategies to overcome challenges faced during clinical research taking place inresource constrained
VectorDisk: a microfluidic platform integrating diagnostic markers for evidence-based mosquito control (Publications)
Effective mosquito monitoring relies on the accurate identification and characterization of the target population. Since this process requires specialist knowledge and equipment that is not widely ava