Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of <em>Plasmodium falciparum</em> dUTP... (Publications)
The ubiquitous enzyme dUTP nucleotidohydrolase (dUTPase) catalyses the hydrolysis of dUTP to dUMP and can be considered as the first line of defence against incorporation of uracil into DNA. Inhibitio
Ozone exposure assessment in a southern California community (Publications)
An ozone exposure assessment study was conducted in a Southern California community. The Harvard ozone passive sampler was used to monitor cohorts of 22 and 18 subjects for 8 weeks during the spring a
Glutathione transferase (GSTM1) null genotype, smoking, and prevalence of colorectal adenomas (Publications)
Colorectal cancer is caused by environmental exposures and genetic predisposition. However, little is known of hereditary factors that influence development of common, non-Mendelian forms of this canc
Alcohol and smoking in relation to the prevalence of adenomatous colorectal polyps detected at sigmoidoscopy (Publications)
Cigarette smoking has been associated with adenomatous polyps of the large bowel but not with increased risk of colorectal cancer. Giovannucci et al recently proposed a hypothesis to explain this inco
Chlamydia control activities in Europe: cross-sectional survey (Publications)
BACKGROUND: Chlamydia is the most commonly reported bacterial sexually transmitted infection in Europe. The objective of the Screening for Chlamydia in Europe (SCREen) project was to describe current