Excess mortality during COVID-19 pandemic in Bangladesh: evidence from a rural survey (Publications)
BACKGROUND: The coronavirus disease 2019 (COVID-19) had a profound impact worldwide. In Bangladesh, the official number of deaths for COVID-19 was around 29 000. However, many countries including Bang
Vaccination against dengue fever for travellers (Publications)
Dengue fever, endemic to most tropical and subtropical countries, is a major cause of illness in travellers, but severe dengue, hospitalisation and death are considered rare in this population. Two va
Mixed pesticide sources identified by using wastewater tracers in rivers of South African agricultural catchments (Publications)
The agriculturally dominated region of the Western Cape, South Africa is vulnerable to pesticide pollution. A 2017-2019 pesticide monitoring campaign in the agricultural catchments of Grabouw, Piketbe
The <em>Plasmodium falciparum</em> histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in... (Publications)
The malaria parasite Plasmodium falciparum employs antigenic variation of the virulence factor P. falciparum erythrocyte membrane protein 1 (PfEMP1) to escape adaptive immune responses during blood in
Single- and two-pollutant concentration-response functions for PM2.5 and NO2 for quantifying mortality burden in health impact assessments (Publications)
OBJECTIVE: Health Impact Assessments (HIAs) for air pollutant mixtures are challenging because risk estimates are primarily derived from single-pollutant models. Combining risk estimates from multiple
AnophelesModel: an R package to interface mosquito bionomics, human exposure and intervention effects with models of malaria intervention impact (Publications)
In recent decades, field and semi-field studies of malaria transmission have gathered geographic-specific information about mosquito ecology, behaviour and their sensitivity to interventions. Mathemat
Awareness, treatment, and control among adults living with arterial hypertension or diabetes mellitus in two rural districts in Lesotho (Publications)
In Lesotho, the hypertension and diabetes care cascades are unknown. We measured awareness, treatment, and control of hypertension and diabetes among adults ≥18 years and identified factors associated
Resource use and costs of investigator-sponsored randomised clinical trials in Switzerland, Germany and the United Kingdom: a meta-research study (Publications)
BACKGROUND: Conducting high-quality randomised clinical trials (RCTs) is challenging and resource intensive. Funders and academic investigators depend on limited financial resources and, therefore, ne
Modeling transmission mechanism to infer treatment efficacy of different drugs and combination therapy against <em>Trichuris trichiura</em> (Publications)
Trichuris trichiura is one of four soil-transmitted helminth species that, collectively, are responsible for a considerable public health burden. The World Health Organization recommends preventive ch
Addressing the intracellular vestibule of the plasmodial lactate transporter PfFNT by p-substituted inhibitors amplifies <em>in vitro</em> activity (Publications)
Inhibition of the lactate transporter PfFNT is a valid novel mode of action against malaria parasites. Current pyridine-substituted pentafluoro-3-hydroxy-pent-2-en-1-ones act as substrate analogs with
