Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands (Publications)
BACKGROUND: Conventionally, human monocyte sub-populations are classified according to surface marker expression into classical (CD14(++)CD16(-)), intermediate (CD14(++)CD16(+)) and non-classical (CD1
Ultra-sensitive detection of <em>Plasmodium falciparum</em> by amplification of multi-copy subtelomeric targets (Publications)
BACKGROUND: Planning and evaluating malaria control strategies relies on accurate definition of parasite prevalence in the population. A large proportion of asymptomatic parasite infections can only b
Quality control in the diagnosis of <em>Trichuris trichiura</em> and <em>Ascaris lumbricoides</em> using the Kato-Katz technique: experience from... (Publications)
BackgroundAn accurate diagnosis of soil-transmitted helminthiasis is important for individual patient management, for drug efficacy evaluation and for monitoring control programmes. The Kato-Katz tech
Comparison of detection methods to estimate asexual <em>Plasmodium falciparum</em> parasite prevalence and gametocyte carriage in a community survey... (Publications)
BACKGROUND: The use of molecular techniques to detect malaria parasites has been advocated to improve the accuracy of parasite prevalence estimates, especially in moderate to low endemic settings. Mol
Evaluation of the <em>in vitro</em> trypanocidal activity of methylated flavonoid constituents of <em>Vitex simplicifolia</em> leaves (Publications)
BACKGROUND: Trypanosomiasis is a neglected tropical disease with complex clinical manifestations, tedious diagnosis, and difficult treatments. The drugs available for the treatment of this endemic dis