Identification of a family of species-selective complex I inhibitors as potential anthelmintics (Publications)
Soil-transmitted helminths (STHs) are major pathogens infecting over a billion people. There are few classes of anthelmintics and there is an urgent need for new drugs. Many STHs use an unusual form o
Health workers' perspectives on school-based mass drug administration control programs for soil-transmitted helminthiasis and schistosomiasis in Ogun... (Publications)
BACKGROUND: Soil-transmitted helminthiasis (STH) and schistosomiasis (SCH) are among the most prevalent neglected tropical diseases (NTDs), affecting 1.5 billion globally, with a significant burden in
Exploring evidence use and capacity for health services management and planning in Swiss health administrations: a mixed-method interview study (Publications)
BACKGROUND: Health administrations require evidence, meaning robust information, data, and research, on health services and systems. Little is known about the resources and processes available within
Diagnostic accuracy of a sequence-specific <em>Mtb</em>-DNA hybridization assay in urine: a case-control study including subclinical TB cases (Publications)
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains one of the deadliest infectious diseases globally. Timely diagnosis is a key step in the management of TB patients and in the preve
Comparison for the effects of different components of temperature variability on mortality: a multi-country time-series study (Publications)
BACKGROUND: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. OBJECTIVES: We aimed to asse
Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in <em>Plasmodium falciparum</em>... (Publications)
BACKGROUND: Emerging artemisinin partial resistance and diagnostic resistance are a threat to malaria control in Africa. Plasmodium falciparum kelch13 (k13) propeller-domain mutations that confer arte
Experiences of community health workers on adopting mHealth in rural Malawi: a qualitative study (Publications)
BACKGROUND: The use of mobile health technology (mHealth) by community health workers (CHWs) can strengthen community-based service delivery and improve access to and quality of healthcare. OBJECTIVE:
<em>In vivo</em> antimalarial efficacy of <em>Artemisia afra</em> powder suspensions (Publications)
BACKGROUND: A global death toll of 608,000 in 2022 and emerging parasite resistance to artemisinin, the mainstay of antimalarial chemotherapy derived from the Chinese herb Artemisia annua, urge the de
Climate change, malaria and neglected tropical diseases: a scoping review (Publications)
To explore the effects of climate change on malaria and 20 neglected tropical diseases (NTDs), and potential effect amelioration through mitigation and adaptation, we searched for papers published fro
Recovery of left ventricular systolic function in peripartum cardiomyopathy: an observational study from rural Tanzania (Publications)
BACKGROUND: The aim of this study was to evaluate the recovery rate of the left ventricular systolic function of women diagnosed with peripartum cardiomyopathy receiving specialized care in rural Tanz
