Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the plasmodium life cycle (Publications)
Quinolines are excellent ligands for metal coordination and are deployed as drugs for malaria treatment. There is a growing body of evidence indicating that metal complexes can be conjugated with anti
Metabolism of (R)-praziquantel versus the activation of a parasite transient receptor potential melastatin ion channel (Publications)
Praziquantel (PZQ) is an essential anthelmintic drug recently established to be an activator of a Transient Receptor Potential Melastatin (TRPMPZQ) ion channel in trematode worms. Bioinformatic, mutag
Sporozoite immunization: innovative translational science to support the fight against malaria (Publications)
INTRODUCTION: Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A
Can working with the private for-profit sector improve utilization of quality health services by the poor? A systematic review of the literature (Publications)
BACKGROUND: There has been a growing interest in the role of the private for-profit sector in health service provision in low- and middle-income countries. The private sector represents an important s
Primary health care supervision in developing countries (Publications)
OBJECTIVES: To (a) summarise opinion about what supervision of primary health care is by those advocating it; (b) compare these features with reports describing supervision in practice; and (c) to app