Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
Praziquantel (PZQ) is the only available drug to treat schistosomiasis, and since its large scale use might be associated with the onset of resistance, new antischistosomal drugs should be developed.
School distribution as keep-up strategy to maintain universal coverage of long-lasting insecticidal nets: implementation and results of a program in... (Publications)
Tanzania successfully scaled up coverage of long-lasting insecticidal nets (LLINs) through mass campaigns. To sustain these gains, a school-based approach was piloted in the country's Southern Zone st
Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
In Lao PDR, detailed investigations on Opisthorchis viverrini are scarce. The objective was to document epidemiological features of O. viverrini infections in a highly endemic district. A random sampl
Combining synthetic human odours and low-cost electrocuting grids to attract and kill outdoor-biting mosquitoes: field and semi-field evaluation of an... (Publications)
BACKGROUND: On-going malaria transmission is increasingly mediated by outdoor-biting vectors, especially where indoor insecticidal interventions such as long-lasting insecticide treated nets (LLINs) a
Efficacy of praziquantel against <em>Schistosoma mekongi </em>and <em>Opisthorchis viverrini</em>: a randomized, single-blinded dose-comparison trial (Publications)
BACKGROUND: Schistosomiasis and opisthorchiasis are of public health importance in Southeast Asia. Praziquantel (PZQ) is the drug of choice for morbidity control but few dose comparisons have been mad
Severe morbidity due to <em>Opisthorchis viverrini</em> and <em>Schistosoma mekongi</em> infection in Lao PDR (Publications)
We assessed morbidity due to Opisthorchis viverrini and Schistosoma mekongi infections in 243 individuals in Lao PDR. Morbidity was associated with O. viverrini infection intensity. Co-infection with
<em>Opisthorchis viverrini</em>: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro (Publications)
The tegumental changes in adult Opisthorchis viverrini induced by tribendimidine were analyzed by scanning electron microscopy (SEM). We exposed O. viverrini to tribendimidine at a concentration of 10
<em>CHI3L1 </em>polymorphisms, cord blood YKL-40 levels and later asthma development (Publications)
BACKGROUND: Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never
Subtle to severe hepatobiliary morbidity in <em>Opisthorchis viverrini </em>endemic settings in Southern Laos (Publications)
Evidence of severe hepatobiliary morbidity associated with Opisthorchis viverrini liver fluke infection including cholangiocarcinoma (CCA) is scarce in Laos although O. viverrini infection is highly p
