Operational differences between product development partnership, pharmaceutical industry, and investigator initiated clinical trials (Publications)
Medicine development is a lengthy endeavour. Increasing regulatory stringency and trial complexity might lead to reduced efficiency, dwindled output, and elevated costs. However, alternative models ar
Impact of population aging on future temperature-related mortality at different global warming levels (Publications)
Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on th
Health system utilization and perceived quality among adults in Lao PDR: evidence from a nationally representative phone survey (Publications)
BACKGROUND: The World Health Organization (WHO) defines quality health services as being effective, safe, people-centered, timely, equitable, integrated and efficient. It is critical to understand peo
Predicting hosts and cross-species transmission of <em>Streptococcus agalactiae</em> by interpretable machine learning (Publications)
BACKGROUND: Streptococcus agalactiae, commonly known as Group B Streptococcus (GBS), exhibits a broad host range, manifesting as both a beneficial commensal and an opportunistic pathogen across variou
Drug repurposing in the chemotherapy of infectious diseases (Publications)
Repurposing is a universal mechanism for innovation, from the evolution of feathers to the invention of Velcro tape. Repurposing is particularly attractive for drug development, given that it costs mo
Accessibility of malaria commodities in Geita District Council, mainland Tanzania: the experiences from healthcare providers and clients (Publications)
BACKGROUND: Access to essential malaria commodities is a cornerstone in malaria control. However optimal availability and access to essential malaria commodities remain a challenge in Tanzania. Theref
Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: protocol for an open-label randomized... (Publications)
BACKGROUND: In absence of contraindications, same-day initiation (SDI) of antiretroviral therapy (ART) is recommended for people testing HIV-positive who are ready to start treatment. Until 2021, Worl
International study of childhood leukemia in residences near electrical transformer rooms (Publications)
OBJECTIVES: New epidemiologic approaches are needed to reduce the scientific uncertainty surrounding the association between extremely low frequency magnetic fields (ELF-MF) and childhood leukemia. Wh
Simultaneous alleviation of verification and reference standard biases in a community-based tuberculosis screening study using Bayesian latent class... (Publications)
BACKGROUND: Estimation of prevalence and diagnostic test accuracy in tuberculosis (TB) prevalence surveys suffer from reference standard and verification biases. The former is attributed to the imperf