Identifying key factors of the transmission dynamics of drug-resistant malaria (Publications)
Development of resistance to malaria treatments remains a great threat to continued malaria burden reduction and elimination. Quantifying the impact of key factors which increase the emergence and spr
Comparison of different drug regimens for the treatment of loiasis-A TropNet retrospective study (Publications)
BACKGROUND: Loa loa infection is endemic in limited areas of West-Central Africa. Loiasis has been associated with excess mortality, but clinical studies on its treatment are scant, particularly outsi
Assessment of tegumental damage to <em>Schistosoma mansoni </em>and <em>S. haematobium </em>after <em>in vitro</em> exposure to ferrocenyl,... (Publications)
BACKGROUND: Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it. We recently demonstrated that ferrocenyl, ruthenoce
Synthesis of jacaranone-derived nitrogenous cyclohexadienones and their antiproliferative and antiprotozoal activities (Publications)
The cytotoxic and antiprotozoal activities of the phytoquinoide, jacaranone, and related compounds have been an ongoing topic in recent drug discovery. Starting from the natural product-derived cycloh
What conditions enable decentralization to improve the health system? Qualitative analysis of perspectives on decision space after 25 years of... (Publications)
BACKGROUND: Decentralization is promoted as a strategy to improve health system performance by bringing decision-making closer to service delivery. Some studies have investigated if decentralization a
Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study (Publications)
BACKGROUND: As a result of epidemiological transition, the health systems of low- and middle-income countries are increasingly faced with a dual disease burden of infectious diseases and emerging non-
Using open street map data in environmental exposure assessment studies: Eastern Massachusetts, Bern region, and South Israel as a case study (Publications)
There is an increase in the awareness of the importance of spatial data in epidemiology and exposure assessment (EA) studies. Most studies use governmental and ordnance surveys, which are often expens
China's tuberculosis epidemic stems from historical expansion of four strains of <em>Mycobacterium tuberculosis</em> (Publications)
A small number of high-burden countries account for the majority of tuberculosis cases worldwide. Detailed data are lacking from these regions. To explore the evolutionary history of Mycobacterium tub
The promise, problems and pitfalls of mass drug administration for malaria elimination: a qualitative study with scientists and policymakers (Publications)
Background: The emergence of artemisinin resistance in the Greater Mekong Subregion (GMS) has prompted urgent containment measures. One possible approach is mass drug administration (MDA). This articl
