Influence of parasite density and sample storage time on the reliability of <em>Entamoeba histolytica</em>-specific PCR from formalin-fixed and... (Publications)
We report on the reliability of polymerase chain reaction (PCR) for the detection of Entamoeba histolytica from formalin-fixed, paraffin-embedded tissue in comparison with microscopy and have determin
Outbreak of <em>Cryptosporidium hominis</em> following river flooding in the city of Halle (Saale), Germany, August 2013 (Publications)
BACKGROUND: During weeks 32-33, 2013, 24 cases of cryptosporidiosis were notified in the city of Halle (annual mean 2008-2012: 9 cases). We investigated the outbreak to identify the source and recomme
Time-course of upper respiratory tract viral infection and COPD exacerbation (Publications)
Viral respiratory tract infections have been implicated as the predominant risk factor for acute exacerbations of COPD (AECOPD). We aimed to evaluate, longitudinally, the association between upper res
Impact of the warm summer 2015 on emergency hospital admissions in Switzerland (Publications)
BACKGROUND: Only a few studies have examined the impact of a particular heat event on morbidity. The aim of this study was to evaluate the impact of the warm summer 2015 on emergency hospital admissio
Five-year impact of different multi-year mass drug administration strategies on childhood <em>Schistosoma mansoni</em>-associated morbidity: a... (Publications)
The WHO recommends mass treatment with praziquantel as the primary approach for Schistosoma mansoni-related morbidity control in endemic populations. The Schistosomiasis Consortium for Operational Res
Safety profile of the meningococcal conjugate vaccine (Menafrivac™) in clinical trials and vaccination campaigns: a review of published studies (Publications)
The study aimed to assess the capacity of AEFI surveillance during vaccination campaigns with the new conjugate meningitis vaccine (MenAfrivac). A systematic review of studies on MenAfrivac published
Mechanistic dose-response modelling of animal challenge data shows that intact skin is a crucial barrier to leptospiral infection (Publications)
Leptospirosis is a widespread and potentially life-threatening zoonotic disease caused by spirochaetes of the genus Leptospira. Humans become infected primarily via contact with environmental reservoi
Targeting a large active site: structure-based design of nanomolar inhibitors of <em>Trypanosoma brucei </em>trypanothione reductase (Publications)
Trypanothione reductase (TR) plays a key role in the unique redox metabolism of trypanosomatids, the causative agents of human African trypanosomiasis (HAT), Chagas' disease, and leishmaniases. Introd
