Inhibitors of PEX14 disrupt protein import into glycosomes and kill <em>Trypanosoma</em> parasites (Publications)
The parasitic protists of the Trypanosoma genus infect humans and domestic mammals, causing severe mortality and huge economic losses. The most threatening trypanosomiasis is Chagas disease, affecting
A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now (Publications)
In 2001, the World Health Assembly (WHA) passed the landmark WHA 54.19 resolution for global scale-up of mass administration of anthelmintic drugs for morbidity control of schistosomiasis and soil-tra
Diagnostic delay and associated factors among patients with pulmonary tuberculosis in Dar es Salaam, Tanzania (Publications)
BACKGROUND: Tanzania is among the 30 countries with the highest tuberculosis (TB) burdens. Because TB has a long infectious period, early diagnosis is not only important for reducing transmission, but
Modelling the health and economic impacts of the elimination of river blindness (onchocerciasis) in Africa (Publications)
BACKGROUND: Onchocerciasis (river blindness) is endemic mostly in remote and rural areas in sub-Saharan Africa. The treatment goal for onchocerciasis has shifted from control to elimination in Africa.
International workshop on insecticide resistance in vectors of arboviruses, December 2016, Rio de Janeiro, Brazil (Publications)
Vector-borne diseases transmitted by insect vectors such as mosquitoes occur in over 100 countries and affect almost half of the world's population. Dengue is currently the most prevalent arboviral di
The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR (Publications)
Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, is central to the pathogenesis of the chronic necrotizing skin disease Buruli ulcer (BU). Here we show that mycolactone acts as
