State of the science and future directions for research on HIV and cancer: summary of a joint workshop sponsored by IARC and NCI (Publications)
An estimated 38 million people live with human immunodeficiency virus (HIV) worldwide and are at excess risk for multiple cancer types. Elevated cancer risks in people living with HIV (PLWH) are drive
Anna K. H. Hirsch: drug design and optimisation to disarm dangerous germs (Publications)
Anna K. H. Hirsch, Professor and Head of the Department of Drug Design and Optimisation at the Helmholtz Institute for Pharmaceutical Research in Saarbrücken (HIPS), Germany, is dedicated to fighting
Jonathan L. Vennerstrom: I was standing on the shoulders of giants (Publications)
Jonathan L. Vennerstrom grew up in Ethiopia, where he was witness to the effects of leprosy and other infectious diseases of poverty on the local population. After his studies in organic chemistry, he
Kelly Chibale: learning to fail your way to success (Publications)
A portrait is given of Professor Kelly Chibale, the driving force behind H3D, the drug discovery and development centre at the University of Cape Town, South Africa. He is dedicated to the development
Basel: a hotspot for drug discovery and development against poverty-related diseases (Publications)
In discussion with Lukas Meier from the Swiss Tropical and Public Health Institute (Swiss TPH), Lutz Hegemann, Head of Novartis Global Health and Sustainability and Marcel Tanner, President of the Swi
Repurposing of tuberculosis drug candidates for the treatment of <em>Mycobacterium ulcerans</em> disease (Publications)
Buruli ulcer (BU) is a chronic necrotizing skin disease caused by Mycobacterium ulcerans. Historically, the disease was treated by surgical excision of the skin lesions, until an 8-week combination th
Quinacrine - the winding road from the most important antimalarial of its time to an indispensable antiparasitic (orphan) drug of our days (Publications)
Quinacrine, the main antimalarial drug during World War II, has had a chequered history that included the successful repurposing as an intrapleural sclerosant for the treatment of malignant pleural ef
Repurposing know-how for drug development: case studies from the Swiss Tropical and Public Health Institute (Publications)
In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a strategy that capitalises on previously
Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases (Publications)
Thanks to its expertise in clinical research, epidemiology, infectious diseases, microbiology, parasitology, public health, translational research and tropical medicine, coupled with deeply rooted par
The first case series of malaria overlapped with COVID-19 in Iran (Publications)
Introduction: Although indigenous malaria cases have dramatically declined over the past decades, the COVID pandemic has continued to affect the programs designed to combat malaria, particularly in th
