Synthesis and antiprotozoal activity of dicationic 2, 6-diphenylpyrazines and aza-analogues (Publications)
Dicationic 2,6-diphenylpyrazines, aza-analogues and prodrugs were synthesized; evaluated for DNA affinity, activity against Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.)
Consensus standards for introductory e-learning courses in human participants research ethics (Publications)
This paper reports the results of a workshop held in January 2013 to begin the process of establishing standards for e-learning programmes in the ethics of research involving human participants that c
Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom (Publications)
omega-Aminoacyl and -alkyl derivatives of 4-(4-methylpiperazin-1-yl)bicyclo[2.2.2]octan-2-amines and of 5-(4-methylpiperazin-1-yl)-2-azabicyclo[3.2.2]nonanes were prepared and their activities were ex
Disposition of mefloquine and enpiroline is highly influenced by a chronic <em>Schistosoma mansoni</em> infection (Publications)
Chronic Schistosoma mansoni infections lead to severe tissue destructions of the gut wall and liver and can influence drug disposition. This study aimed to investigate the impact of a chronic S. manso
High throughput multiplex assay for species identification of Papua New Guinea malaria vectors: members of the <em>Anopheles punctulatus</em>... (Publications)
Malaria and filariasis are transmitted in the Southwest Pacific region by Anopheles punctulatus sibling species including An. punctulatus, An. koliensis, the An. farauti complex 1-8 (includes An. hine
Structure-activity relationship studies of pyrrolone antimalarial agents (Publications)
Previously reported pyrrolones, such as TDR32570, exhibited potential as antimalarial agents; however, while these compounds have potent antimalarial activity, they suffer from poor aqueous solubility
