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1. New drugs for the treatment of human African trypanosomiasis: research and development (Publications)

   New drugs for the treatment of human African trypanosomiasis: research and development

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   Chemotherapy of human African trypanosomiasis is problematic because of the high frequency of severe adverse events, the long duration and high cost of treatment, and an increasing number of treatment

2. Topoisomerases in kinetoplastids (Publications)

   Topoisomerases in kinetoplastids

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   Topoisomerases are enzymes that mediate topological changes in DNA that are essential for nucleic acid biosynthesis and for cell survival. The kinetoplastid protozoa, which include pathogenic trypanos

3. Improving efficiency and quality in clinical trials in sub-Saharan Africa (Publications)

   Improving efficiency and quality in clinical trials in sub-Saharan Africa

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4. Clinical research data management: solutions for low-resource settings (Publications)

   Clinical research data management: solutions for low-resource settings

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5. Human African trypanosomiasis (Publications)

   Human African trypanosomiasis

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6. An unusual type IB topoisomerase from African trypanosomes (Publications)

   An unusual type IB topoisomerase from African trypanosomes

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   African trypanosomes are ancient eukaryotes that cause lethal disease in humans and cattle. Available drugs are inadequate and the need for new therapeutic targets is great. Trypanosoma brucei and rel

7. Antitrypanosomal activity of pyrrolidinyl-substituted fluoroquinolones (Publications)

   Antitrypanosomal activity of pyrrolidinyl-substituted fluoroquinolones

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8. Safety and efficacy of fexinidazole against rhodesiense human African trypanosomiasis: approach to conducting a clinical trial for a very rare,... (Publications)

   Safety and efficacy of fexinidazole against rhodesiense human African trypanosomiasis: approach to conducting a clinical trial for a very rare, neglected disease

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9. Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis) (Publications)

   Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis)

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   OBJECTIVES: To estimate the frequency and evolution of heart involvement in human African trypanosomiasis (HAT) using electrocardiogram (ECG) findings; to describe these findings and to assess the fre

10. Current chemotherapy of human African trypanosomiasis (Publications)

    Current chemotherapy of human African trypanosomiasis

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