Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection (Publications)
The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,13
CD38 expression by antigen-specific CD4 t cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load... (Publications)
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, t
Der lange Weg zur ersten Impfung gegen Malaria (Publications)
Ein historisches Ereignis nach einem langen Weg: Die Weltgesundheitsorganisation hat jüngst den Einsatz des ersten Impfstoffes gegen Malaria zum breitflächigen Einsatz bei Kindern in den betroffenen
Le long chemin vers le premier vaccin antipaludique (Publications)
Un événement historique après un long chemin: l’Organisation mondiale de la santé a récemment recommandé l’utilisation à grande échelle du premier vaccin antipaludique chez les enfants des pays concer
A systematic molecular epidemiology screen reveals numerous human immunodeficiency virus (HIV) type 1 superinfections in the Swiss HIV Cohort Study (Publications)
BACKGROUND: Studying HIV-1 superinfection is important to understand virus transmission, disease progression, and vaccine design. But detection remains challenging, with low sampling frequencies, and
Drug resistance in leprosy: an update following 70 years of chemotherapy (Publications)
Leprosy is one of the oldest infectious diseases, reported for more than 2,000 years. Leprosy elimination goal as a public health problem set by the World Health Organization, aiming for a global prev
Parental and provider vaccine hesitancy and non-timely childhood vaccination in Switzerland (Publications)
OBJECTIVE: Although medical providers are a trusted vaccination information source for parents, they do not universally support vaccination. Complementary medicine (CM) providers are particularly like
Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data (Publications)
The Infectious Diseases Data Observatory (IDDO, https://www.iddo.org) has launched a clinical data platform for the collation, curation, standardisation and reuse of individual participant data (IPD)
Diagnoses and procedures of inpatients with female genital mutilation/cutting in Swiss university hospitals: a cross-sectional study (Publications)
BACKGROUND: Female genital mutilation/cutting (FGM/C) can result in short and long-term complications, which can impact physical, psychological and sexual health. Our objective was to obtain descripti