Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord blood (Publications)
BACKGROUND: Recent studies indicate that prenatal vitamin D intake may protect against the development of atopic diseases in young children. Vitamin D has been shown to induce tolerogenic antigen-pres
Paraspinal abscess secondary to tuberculous spondylitis diagnosed by Xpert MTB/RIF assay in rural Tanzania (Publications)
A 31-year-old HIV-negative man presented to our clinic with a 6-month history of back pain and a swelling at the back. Radiological studies revealed lumbar vertebral destruction. Ultrasound of the mas
Epidemiology of malaria in the Papua New Guinean highlands (Publications)
Objectives To conduct an in-depth investigation of the epidemiology of malaria in the Papua New Guinea (PNG) highlands and provide a basis for evidence-based planning and monitoring of intensified mal
Effects of inflammation and <em>Plasmodium falciparum</em> infection on soluble transferrin receptor and plasma ferritin concentration in different... (Publications)
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to
Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in south Africa (Publications)
We studied the immune response after starting antiretroviral treatment (ART) in 15,646 HIV-infected patients with or without tuberculosis (TB) at presentation in 3 ART programs in South Africa between
Optimization of the electrophile of chloronitrobenzamide leads active against <em>Trypanosoma brucei</em> (Publications)
We previously reported the phenylchloronitrobenzamides (PCNBs), a novel class of compounds active against the species of trypanosomes that cause Human African Trypanosomiasis (HAT). Herein, we explore
Evidence for diversifying selection in a set of <em>Mycobacterium tuberculosis</em> genes in response to antibiotic- and nonantibiotic-related... (Publications)
Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculo