Sequence diversity in the <em>pe_pgrs</em> genes of <em>Mycobacterium tuberculosis</em> is independent of human T cell recognition (Publications)
The Mycobacterium tuberculosis genome includes the large family of pe_pgrs genes, whose functions are unknown. Because of precedents in other pathogens in which gene families showing high sequence var
EMF monitoring - concepts, activities, gaps and options (Publications)
Exposure to electromagnetic fields (EMF) is a cause of concern for many people. The topic will likely remain for the foreseeable future on the scientific and political agenda, since emissions continue
High blood pressure and long-term exposure to indoor noise and air pollution from road traffic (Publications)
BACKGROUND: Traffic noise has been associated with prevalence of hypertension, but reports are inconsistent for blood pressure (BP). People's noise exposure indoors might be essential to ascertain eff
Modeling the cost effectiveness of malaria control interventions in the highlands of western Kenya (Publications)
INTRODUCTION: Tools that allow for in silico optimization of available malaria control strategies can assist the decision-making process for prioritizing interventions. The OpenMalaria stochastic simu
Can action research strengthen district health management and improve health workforce performance? A research protocol (Publications)
INTRODUCTION: The single biggest barrier for countries in sub-Saharan Africa (SSA) to scale up the necessary health services for addressing the three health-related Millennium Development Goals and ac
Cause-specific mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
BACKGROUND: Because most deaths in Africa and Asia are not well documented, estimates of mortality are often made using scanty data. The INDEPTH Network works to alleviate this problem by collating de
Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of <em>Trypanosoma brucei</em> (Publications)
Eukaryotic elongation factor 1A (eEF1A) is the only protein modified by ethanolamine phosphoglycerol (EPG). In mammals and plants, EPG is attached to conserved glutamate residues located in eEF1A doma
Discovery and evaluation of thiazinoquinones as anti-protozoal agents (Publications)
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 muM)
Weather and mortality: a 10 year retrospective analysis of the Nouna Health and Demographic Surveillance System, Burkina Faso (Publications)
Background: A growing body of evidence points to the emission of greenhouse gases from human activity as a key factor in climate change. This in turn affects human health and wellbeing through consequ
Changing patterns of health in communities impacted by a bioenergy project in northern Sierra Leone (Publications)
Large private sector investments in low- and middle-income countries are often critically evaluated with regards to their environmental, social, human rights, and health impacts. A health impact asses
