Mefloquine interferes with glycolysis in schistosomula of <em>Schistosoma mansoni</em> via inhibition of enolase (Publications)
SUMMARYThe antimalarial drug mefloquine has promising antischistosomal properties killing haematophagous adult schistosomes as well as schistosomula. The mode of action and involved drug targets of me
Isothermal microcalorimetry to study drugs against <em>Schistosoma mansoni</em> (Publications)
Background: Alternative antischistosomal drugs are required since praziquantel is virtually the only drug available for treatment and morbidity control of schistosomiasis. Manual microscopic reading i
Imaging of <em>Plasmodium</em> liver stages to drive next-generation antimalarial drug discovery (Publications)
Most malaria drug development focuses on parasite stages detected in red blood cells, even though to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic fo