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1. Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? (Publications)

   Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors?

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   BACKGROUND: Alterations in heart rate variability (HRV) are a potential link between exposure to traffic-related air pollution and cardiovascular mortality. OBJECTIVES: We investigated whether long-te

2. Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project (Publications)

   Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project

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3. Traffic-related air pollution correlates with adult-onset asthma among never-smokers (Publications)

   Traffic-related air pollution correlates with adult-onset asthma among never-smokers

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   BACKGROUND: Traffic-related pollution is associated with asthma onset in children. Its effect on adult-onset asthma is poorly investigated. OBJECTIVE: We used the SAPALDIA cohort study to investigate

4. Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of... (Publications)

   Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of particulate matter pollution in the Swiss SAPALDIA regions

   Relevanz:

   BACKGROUND: Land Use Regression (LUR) is a popular method to explain and predict spatial contrasts in air pollution concentrations, but LUR models for ultrafine particles, such as particle number conc

5. Authors' reply to "Gold stage 1 is crying wolf" by PL Enright (Publications)

   Authors' reply to "Gold stage 1 is crying wolf" by PL Enright

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6. Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction... (Publications)

   Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction analysis

   Relevanz:

   Background: Both air pollution and genetic variation have been shown to affect lung function. Their interaction has not been studied on a genome-wide scale to date. Objectives: We aimed to identify, i

7. Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)

   Genome-wide association and functional follow-up reveals new loci for kidney function

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   Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s

8. Reduced exposure to PM10 and attenuated age-related decline in lung function (Publications)

   Reduced exposure to PM10 and attenuated age-related decline in lung function

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   BACKGROUND: Air pollution has been associated with impaired health, including reduced lung function in adults. Moving to cleaner areas has been shown to attenuate adverse effects of air pollution on l

9. Early menarche and new onset of asthma: results from the SAPALDIA cohort study (Publications)

   Early menarche and new onset of asthma: results from the SAPALDIA cohort study

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10. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)

    1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

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    HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re