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1. Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project (Publications)

   Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project

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2. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies (Publications)

   Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

   Relevanz:

   BACKGROUND: Epigenetic variations in peripheral blood have potential as biomarkers for disease. This systematic review assesses the association of lung function and chronic obstructive pulmonary disea

3. Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)

   Infectious diseases are associated with carotid intima media thickness in adolescence

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   OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious

4. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Publications)

   Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

   Relevanz:

   Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals

5. Land use regression models for ultrafine particles in six European areas (Publications)

   Land use regression models for ultrafine particles in six European areas

   Relevanz:

   Long-term ultrafine particle (UFP) exposure estimates at a fine spatial scale are needed for epidemiological studies. Land use regression (LUR) models were developed and evaluated for six European are

6. The adverse impact of obesity on heart rate variability is modified by a <em>NFE2L2 </em>gene variant: the SAPALDIA Cohort (Publications)

   The adverse impact of obesity on heart rate variability is modified by a <em>NFE2L2 </em>gene variant: the SAPALDIA Cohort

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   BACKGROUND: Overweight has been associated with an increase in inflammatory markers and with an imbalance in the autonomic nervous system, such as a decrease in heart rate variability (HRV). In this s

7. Associations between domains of physical activity, sitting time, and different measures of overweight and obesity (Publications)

   Associations between domains of physical activity, sitting time, and different measures of overweight and obesity

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8. Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland (Publications)

   Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland

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   Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses o

9. Asthma, COPD and overlap syndrome: a longitudinal study in young European adults (Publications)

   Asthma, COPD and overlap syndrome: a longitudinal study in young European adults

   Relevanz:

   We compared risk factors and clinical characteristics, 9-year lung function change and hospitalisation risk across subjects with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrom

10. Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort (Publications)

    Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort

    Relevanz:

    Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We