Subtle to severe hepatobiliary morbidity in <em>Opisthorchis viverrini </em>endemic settings in Southern Laos (Publications)
Evidence of severe hepatobiliary morbidity associated with Opisthorchis viverrini liver fluke infection including cholangiocarcinoma (CCA) is scarce in Laos although O. viverrini infection is highly p
<em>CHI3L1 </em>polymorphisms, cord blood YKL-40 levels and later asthma development (Publications)
BACKGROUND: Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never
The genetic architecture of type 2 diabetes (Publications)
The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association st
Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
Praziquantel (PZQ) is the only available drug to treat schistosomiasis, and since its large scale use might be associated with the onset of resistance, new antischistosomal drugs should be developed.
School distribution as keep-up strategy to maintain universal coverage of long-lasting insecticidal nets: implementation and results of a program in... (Publications)
Tanzania successfully scaled up coverage of long-lasting insecticidal nets (LLINs) through mass campaigns. To sustain these gains, a school-based approach was piloted in the country's Southern Zone st
Successful comeback of the single-dose live oral cholera vaccine CVD 103-HgR (Publications)
Effective and easy to administer cholera vaccines are in need more than ever, for at risk populations and travellers alike. In many parts of the world cholera is still endemic, causing outbreaks and c
One Health stakeholder and institutional analysis in Kenya (Publications)
INTRODUCTION: One Health (OH) can be considered a complex emerging policy to resolve health issues at the animal-human and environmental interface. It is expected to drive system changes in terms of n
Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections (Publications)
BACKGROUND: Treatment options for infections with soil-transmitted helminths (STH) - Ascaris lumbricoides, Trichuris trichiura and the two hookworm species, Ancylostoma duodenale and Necator americanu
Effectiveness of Active-Online, an Individually Tailored Physical Activity Intervention, in a Real-Life Setting: Randomized Controlled Trial (Publications)
Background: Effective interventions are needed to reduce the chronic disease epidemic. The Internet has the potential to provide large populations with individual advice at relatively low cost. Object
