Analysis of the <em>Mycobacterium ulcerans</em> genome sequence reveals new loci for variable number tandem repeats (VNTR) typing (Publications)
Screening of the genome sequence of the Mycobacterium ulcerans strain Agy99 from Ghana with tandem repeats finder software revealed 34 novel non-degenerate tandem repeats containing loci suitable for
Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease (Publications)
The integrity of the inner membrane of mitochondria is maintained by a membrane-embedded quality control system that ensures the removal of misfolded membrane proteins. Two ATP-dependent AAA proteases
Differential gene repertoire in <em>Mycobacterium ulcerans</em> identifies candidate genes for patho-adaptation (Publications)
BACKGROUND: Based on large genomic sequence polymorphisms, several haplotypes belonging to two major lineages of the human pathogen Mycobacterium ulcerans could be distinguished among patient isolates
Single nucleotide polymorphisms on the road to strain differentiation in <em>Mycobacterium ulcerans</em> (Publications)
The genomic fine-typing of strains of Mycobacterium ulcerans, the causative agent of the emerging human disease Buruli ulcer, is difficult due to the clonal population structure of geographical lineag
Optimized method for preparation of DNA from pathogenic and environmental mycobacteria (Publications)
Genomic studies on pathogenic and environmental mycobacteria are of growing interest for understanding of their evolution, distribution, adaptation, and host-pathogen interaction. Since most mycobacte
Optimized DNA preparation from mycobacteria (Publications)
Extraction of genomic DNA from mycobacteria requires special consideration because (i) many mycobacterial species exhibit extremely slow growth, and thus produce only small amounts of starting materia
Tuberculosis mortality and living conditions in Bern, Switzerland, 1856-1950 (Publications)
BACKGROUND: Tuberculosis (TB) is a poverty-related disease that is associated with poor living conditions. We studied TB mortality and living conditions in Bern between 1856 and 1950. METHODS: We anal
Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig (Publications)
OBJECTIVE: To investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model. MATERIAL & METHODS: Eighteen soft tiss
