Repository describing an aging population to inform physiologically based pharmacokinetic models considering anatomical, physiological, and biological... (Publications)
BACKGROUND: Aging is characterized by anatomical, physiological, and biological changes that can impact drug kinetics. The elderly are often excluded from clinical trials and knowledge about drug kine
Objectively measured physical activity in population-representative parent-child pairs: parental modelling matters and is context-specific (Publications)
BACKGROUND: Evidence for the context-specific influence of parental modelling on physical activity (PA) in childhood remains inconclusive. This nationwide Swiss study assessed the cross-sectional asso
<em>SERPINA1 </em>methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based... (Publications)
BACKGROUND: The pathophysiological role of SERPINA1 in respiratory health may be more strongly determined by the regulation of its expression than by common genetic variants. A family based study of p
Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission (Publications)
BACKGROUND: Current strategies to control mosquito-transmitted infections use insecticides targeted at various stages of the mosquito life-cycle. Control is increasingly compromised by the evolution o
Evaluation of standard field and laboratory methods to compare protection times of the topical repellents PMD and DEET (Publications)
Mosquitoes are important vectors of pathogens, and travellers to disease endemic countries are advised to avoid bites by applying topical repellents. Topical repellents are typically tested either in
Effect of insecticide-treated bed nets on the dynamics of multiple <em>Plasmodium falciparum</em> infections (Publications)
The rates of acquisition and loss of individual genotypes belonging to the FC27 family of the Plasmodium falciparum merozoite surface protein 2 (msp2) gene were studied in 120 children aged 5 months t