Discovery and characterization of <em>Mycobacterium basiliense</em> sp. nov., a nontuberculous <em>Mycobacterium </em>isolated from human lungs (Publications)
Bacteria belonging to the genus Mycobacterium are predominantly responsible for pulmonary diseases; most notably Mycobacterium tuberculosis causes granulomatous pulmonary infections. Here we describe
Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development (Publications)
Glycosomes evolved as specialized system for glycolysis in trypanosomatids. These organelle rely on protein import to maintain function. A machinery of peroxin (PEX) proteins is responsible for recogn
Dynamics of respiratory symptoms during infancy and associations with wheezing at school age (Publications)
Children with frequent respiratory symptoms in infancy have an increased risk for later wheezing, but the association with symptom dynamics is unknown. We developed an observer-independent method to c
Translating preventive chemotherapy prevalence thresholds for <em>Schistosoma mansoni </em>from the Kato-Katz technique into the point-of-care... (Publications)
BACKGROUND: Intervention guidelines against Schistosoma mansoni are based on the Kato-Katz technique. However, Kato-Katz thick smears show low sensitivity, especially for light-intensity infections. T
Modelling to inform prophylaxis regimens to prevent human rabies (Publications)
BACKGROUND: The Strategic Advisory Group of Experts (SAGE) Working Group on rabies vaccines and immunoglobulins was established in 2016 to develop practical and feasible recommendations for prevention
Drug discovery for kinetoplastid diseases: future directions (Publications)
Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) an
