Determination of optimal diagnostic cut-offs for the Naval Medical Research Centre scrub typhus IgM ELISA in Chiang Rai, Thailand (Publications)
In this diagnostic accuracy study, we evaluated data from 135 febrile patients from Chiang Rai, to determine the optimal optical density (OD) cutoffs for an in-house scrub typhus IgM ELISA. Receiver o
Pharmacokinetics of ascending doses of ivermectin in <em>Trichuris trichiura</em>-infected children aged 2-12 years (Publications)
BACKGROUND: Yearly, millions of children are treated globally with ivermectin mainly for neglected tropical diseases. Anatomical, physiological and biochemical differences between children and adults
Modeling the impact of sterile males on an <em>Aedes aegypti</em> population with optimal control (Publications)
We use partial differential equations to describe the dynamics of an Aedes aegypti mosquito population on an island, and the effects of a sterile male release. The model includes mosquito movement and
Is <em>Opisthorchis viverrini</em> emerging in Cambodia? (Publications)
Opisthorchis viverrini infection is widely prevalent in Southeast Asia. In Cambodia information on this helminth infection is scare. Recent reports suggest that O. viverrini is an emerging public heal
Clinical characteristics and outcome of children hospitalized with scrub typhus in an area of endemicity (Publications)
BACKGROUND: Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS: We recruited 60 febrile pediatric patients with a posit
Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin (Publications)
Herein, we describe a biomimetic entry to (+)-3-hydroxymethylartemisinin (2) as well as to the artemisinin derivatives (+)-3-hydroxymethyl-9-desmethylartemisinin (16) and (+)-3-hydroxymethyl-9-epi-art
Exposure to moderate air pollution and associations with lung function at school-age: a birth cohort study (Publications)
BACKGROUND: Adverse effects of higher air pollution levels before and after birth on subsequent lung function are often reported in the literature. We assessed whether low-to-moderate levels of air po
Evaluation of the sentinel surveillance system for influenza-like illnesses in the Greater Accra region, Ghana, 2018 (Publications)
BACKGROUND: Influenza-like Illness (ILI) is a medical diagnosis of possible influenza or another respiratory illness with a common set of symptoms. The deaths of four schoolchildren, during a pandemic
Measuring mobility, disease connectivity and individual risk: a review of using mobile phone data and mHealth for travel medicine (Publications)
RATIONALE FOR REVIEW: The increasing mobility of populations allows pathogens to move rapidly and far, making endemic or epidemic regions more connected to the rest of the world than at any time in hi
Epidemiological links between malaria parasitaemia and hypertension: findings from a population-based survey in rural Côte d'Ivoire (Publications)
BACKGROUND: Although potential links between malaria parasitaemia and hypertension have been hypothesized, there is paucity of epidemiologic evidence on this link. We investigated in a population-base
