Design, synthesis, and biological evaluation of new 1-(Aryl-1<em>H</em>-pyrrolyl)(phenyl)methyl-1<em>H</em>-imidazole derivatives as antiprotozoal... (Publications)
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently. The new analogs possess
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Publications)
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we
Depression and anxiety symptoms in cardiac patients: a cross-sectional hospital-based study in a Palestinian population (Publications)
BACKGROUND: Mental health problems have an adverse effect on the course of cardiac disease. The integration of their diagnosis and treatment into cardiology care is generally poor. It is particularly
Evaluating next-generation sequencing (NGS) methods for routine monitoring of wild bees: metabarcoding, mitogenomics or NGS barcoding (Publications)
Implementing cost-effective monitoring programs for wild bees remains challenging due to the high costs of sampling and specimen identification. To reduce costs, next generation sequencing (NGS)-based
Spatial variability in air pollution exposure in relation to socioeconomic indicators in nine European metropolitan areas: a study on environmental... (Publications)
A limited number of studies have addressed environmental inequality, using various study designs and methodologies and often reaching contradictory results. Following a standardized multi-city data co
Reference set of <em>Mycobacterium tuberculosis </em>clinical strains: a tool for research and product development (Publications)
The Mycobacterium tuberculosis complex (MTBC) causes tuberculosis (TB) in humans and various other mammals. The human-adapted members of the MTBC comprise seven phylogenetic lineages that differ in th
The effects and contribution of childhood diseases on the geographical distribution of all-cause under-five mortality in Uganda (Publications)
Introduction: Information on the causes of death among under-five children is key in designing and implementation of appropriate interventions. In Uganda, civil death registration is incomplete which
Two successful decades of Swiss collaborations to develop new anti-malarials (Publications)
Over the last two decades there has been a renaissance in the pipeline of new drugs targeting malaria, with the launch of new products that help save the lives of children throughout the world. In add
