Low prevalence of <em>Plasmodium</em> and absence of malaria transmission in Conakry, Guinea: prospects for elimination (Publications)
BACKGROUND: Over the past 15 years, mortality and morbidity due to malaria have been reduced substantially in sub-Saharan Africa and local elimination has been achieved in some settings. This study ad
Annual and seasonal spatial models for nitrogen oxides in Tehran, Iran (Publications)
Very few land use regression (LUR) models have been developed for megacities in low- and middle-income countries, but such models are needed to facilitate epidemiologic research on air pollution. We d
Community knowledge, perceptions, and practices associated with urogenital schistosomiasis among school-aged children in Zanzibar, United Republic of... (Publications)
BACKGROUND: On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand commun
Correlates and outcomes of posttransplant smoking in solid organ transplant recipients: a systematic literature review and meta-analysis (Publications)
BACKGROUND: Despite smoking being an absolute or relative contraindication for transplantation, about 11-40% of all patients continue or resume smoking posttransplant. This systematic review with meta
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond (Publications)
A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, wher
Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy (Publications)
The antiplasmodial activity, DMPK properties, and efficacy of a series of quinoline-4-carboxamides are described. This series was identified from a phenotypic screen against the blood stage of Plasmod
Validation of a rapid rabies diagnostic tool for field surveillance in developing countries (Publications)
BACKGROUND: One root cause of the neglect of rabies is the lack of adequate diagnostic tests in the context of low income countries. A rapid, performance friendly and low cost method to detect rabies
Ebola virus disease, Democratic Republic of the Congo, 2014 (Publications)
During July-November 2014, the Democratic Republic of the Congo underwent its seventh Ebola virus disease (EVD) outbreak. The etiologic agent was Zaire Ebola virus; 66 cases were reported (overall cas
Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a... (Publications)
BACKGROUND: Depression and alcohol use disorder have been shown to be associated with poor adherence to antiretroviral therapy (ART). Studies examining their association with viral suppression in rura
Enhancing collaboration between China and African countries for schistosomiasis control (Publications)
Schistosomiasis remains an important public health issue, with a large number of cases reported across sub-Saharan Africa, and parts of Asia and Latin America. China was once highly endemic, but has m
