Atopic conditions and brain tumor risk in children and adolescents: an international case-control study (CEFALO) (Publications)
BACKGROUND: A number of epidemiological studies indicate an inverse association between atopy and brain tumors in adults, particularly gliomas. We investigated the association between atopic disorders
A profile of travelers - an analysis from a large Swiss travel clinic (Publications)
BACKGROUND: Globally, the Swiss have one of the highest proportions of the population traveling to tropical and subtropical countries. Large travel clinics serve an increasing number of customers with
Fabclavines: bioactive peptide-polyketide-polyamino hybrids from <em>Xenorhabdus</em> (Publications)
The structure of the fabclavines-unique mixtures of nonribosomally derived peptide-polyketide hybrids connected to an unusual polyamino moiety-has been solved by detailed NMR and MS methods. These com
IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo (Publications)
Th17 cells have been recognized as the central effectors in organ-related autoimmune diseases. IL-6 is a key factor that reciprocally regulates Th17 and Foxp3(+) Treg differentiation by inhibition of
Crucial issues in think aloud techniques for cross cultural studies (Publications)
Implementing user-centered design (UCD) principles and conducting usability testing is especially critical in projects where developers do not originate from the deployed environment. However, traditi
Characterisation of a melamino nitroheterocycle as a potential lead for the treatment of human African trypanosomiasis (Publications)
This paper reports an evaluation of a melamine-nitroheterocycle, a potential lead for further development as an agent against human African trypanosomiasis (HAT). Studies on its efficacy, physicochemi
Pharmacokinetic comparison to determine the mechanisms underlying the differential efficacies of cationic diamidines against first- and second-stage... (Publications)
Human African trypanosomiasis (HAT), a neglected tropical disease, is fatal without treatment. Pentamidine, a cationic diamidine, has been used to treat first-stage (hemolymphatic) HAT since the 1940s