Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against <em>Schistosoma mansoni in vitro</em> and<em> in... (Publications)
We studied the antischistosomal activity of betulin, betulinic acid and its 9 triphenylphosphonium derivatives characterized by a covalently linkage of the hydrophobic fragment of triterpenoid at C(2)
Epidemiology of multiple<em> Plasmodium falciparum </em>infections. 4. Age dependence of the multiplicy of <em>Plasmodium falciparum</em> infections... (Publications)
The relationship between age and various malariological indices in the Kilombero valley of Tanzania were examined by compiling data from 6 different community studies carried out between 1989 and 1996
<em>Trypanosoma brucei brucei</em>: a model for cerebral trypanosomiasis in mice--an immunological, histological and electronmicroscopic study (Publications)
The successful induction of cerebral trypanosomiasis in ordinary laboratory mice using Trypanosoma brucei brucei is reported. Sequential studies demonstrated the presence of trypanosomes in the inters
Lipidomics and genomics of <em>Mycobacterium tuberculosis</em> reveal lineage-specific trends in mycolic acid biosynthesis (Publications)
Mycolic acids (MAs) are alpha-alkyl, beta-hydroxy long-chain fatty acids found in abundance in the cell envelope of the Mycobacterium tuberculosis complex (MTBC). MAs form an efficient permeability ba
Characterisation of taxlllaids A-G; natural products from <em>Xenorhabdus indica</em> (Publications)
Six new lipodepsipeptides and an additional linear derivative named taxlllaids A-G (1-7) have been identified in the entomopathogenic bacterium Xenorhabdus indica. The structures of the main compounds
Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds (Publications)
3-Hydroxy-N'-arylidenepropanehydrazonamides represent a new class of antiplasmodial compounds. The two most active phenanthrene-based derivatives showed potent in vitro antiplasmodial activity against