Current allergic asthma and rhinitis: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop). Results from... (Publications)
Total serum IgE, Phadiatop, and the skin prick test (SPT) are commonly used to diagnose atopic diseases. However, no large study has ever been done to test their diagnostic efficiency. We studied the
Is diabetes a risk factor for a severe clinical presentation of dengue? Review and meta-analysis (Publications)
BACKGROUND: The mean age of acute dengue has undergone a shift towards older ages. This fact points towards the relevance of assessing the influence of age-related comorbidities, such as diabetes, on
Predictive value of clinical and laboratory features for the main febrile diseases in children living in Tanzania: a prospective observational study (Publications)
BACKGROUND: To construct evidence-based guidelines for management of febrile illness, it is essential to identify clinical predictors for the main causes of fever, either to diagnose the disease when
Single-dose hepatitis A immunization: 7.5-year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune... (Publications)
BACKGROUND: Universal 2-dose hepatitis A virus (HAV) vaccination of toddlers effectively controls hepatitis A. High vaccine costs, however, impede implementation in endemic countries. To test single-d
The influence of HIV on the evolution of <em>Mycobacterium tuberculosis</em> (Publications)
HIV significantly affects the immunological environment during tuberculosis co-infection, and therefore may influence the selective landscape upon which M. tuberculosis evolves. To test this hypothesi
Efficacy and safety of praziquantel against light infections of <em>Opisthorchis viverrini</em>: a randomised parallel single blind dose-ranging trial (Publications)
BACKGROUND: The liver fluke Opisthorchis viverrini, highly prevalent in Southeast Asia, is an important public health burden, including a risk factor for developing an aggressive bile duct cancer, cho
Elimination of <em>Schistosoma mansoni</em> in infected mice by slow release of artemisone (Publications)
The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging. We sugg