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1. Physiologically based pharmacokinetic modelling to identify pharmacokinetic parameters driving drug exposure changes in the elderly (Publications)

   Physiologically based pharmacokinetic modelling to identify pharmacokinetic parameters driving drug exposure changes in the elderly

   Relevanz:

   BACKGROUND: Medication use is highly prevalent with advanced age, but clinical studies are rarely conducted in the elderly, leading to limited knowledge regarding age-related pharmacokinetic changes.

2. Multiplicity of asymptomatic <em>Plasmodium falciparum </em>infections and risk of clinical malaria: a systematic review and pooled analysis of... (Publications)

   Multiplicity of asymptomatic <em>Plasmodium falciparum </em>infections and risk of clinical malaria: a systematic review and pooled analysis of individual participant data

   Relevanz:

   BACKGROUND: The malaria parasite Plasmodium falciparum holds an extensive genetic polymorphism. In this pooled analysis, we investigate how the multiplicity, i.e. the number of co-infecting clones, in

3. Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study (Publications)

   Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study

   Relevanz:

   BACKGROUND: Primary health care (PHC) is a driving force for advancing towards universal health coverage (UHC). PHC-oriented health systems bring enormous benefits but require substantial financial in

4. "We treat humans, not herds!": a qualitative study of complementary and alternative medicine (CAM) providers' individualized approaches to vaccination... (Publications)

   "We treat humans, not herds!": a qualitative study of complementary and alternative medicine (CAM) providers' individualized approaches to vaccination in Switzerland

   Relevanz:

   Complementary and alternative medicine (CAM) providers' roles in parents' decision-making about vaccinations for their children have only recently begun receiving research attention, despite studies s

5. A single dose of ivermectin is sufficient for strongyloidiasis (Publications)

   A single dose of ivermectin is sufficient for strongyloidiasis

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6. State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional... (Publications)

   State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional study

   Relevanz:

   BACKGROUND: Mass deworming against soil-transmitted helminthiasis, which affects 1 billion of the poorest people globally, is one of the largest public health programmes for neglected tropical disease

7. The challenge of ensuring equity in mass deworming programmes (Publications)

   The challenge of ensuring equity in mass deworming programmes

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8. The role of humidity in associations of high temperature with mortality: a multicountry, multicity study (Publications)

   The role of humidity in associations of high temperature with mortality: a multicountry, multicity study

   Relevanz:

   BACKGROUND: There is strong experimental evidence that physiologic stress from high temperatures is greater if humidity is higher. However, heat indices developed to allow for this have not consistent

9. Old and new powers in development assistance in health (Publications)

   Old and new powers in development assistance in health

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10. The transferability of lipid loci across African, Asian and European cohorts (Publications)

    The transferability of lipid loci across African, Asian and European cohorts

    Relevanz:

    Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populat