Vaccine hesitancy and HPV vaccine uptake among male and female youth in Switzerland: a cross-sectional study (Publications)
OBJECTIVES: Identifying factors associated with human papillomavirus (HPV) vaccine uptake is essential for designing successful vaccination programmes. We aimed to examine the association between vacc
Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12) (Publications)
The catechol derivative RC-12 (WR 27653) (1) is one of the few non-8-aminoquinolines with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) mod
Use of index testing to close the gap in HIV diagnosis among older people in Rwanda: analysis of data from a public health programme (Publications)
BACKGROUND: As Rwanda inches closer to the UNAIDS HIV first 95 of knowing one's HIV status by 2030, finding the remaining HIV-positive individuals could be difficult by use of passive methods. Index t
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 (Publications)
Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibi
Gut microbiota targeted approach in the management of chronic liver diseases (Publications)
The liver is directly connected to the intestines through the portal vein, which enables the gut microbiota and gut-derived products to influence liver health. There is accumulating evidence of decrea
Together yet apart: remedies for tensions between volunteers and health care professionals in inter-professional collaboration (Publications)
While volunteering is an essential factor in service delivery in many societal areas, the inclusion of volunteers in formal settings can also lead to tensions. In this article, we combine the literatu
Inequality in the quality of health services: wealth, content of care, and the price of antenatal consultations in the Democratic Republic of Congo (Publications)
We use unique data on direct observations of patient-provider interactions linked to detailed patient exit interviews and household surveys to study the relationship between patients’ socioeconomic st
Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection (Publications)
The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,13
CD38 expression by antigen-specific CD4 t cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load... (Publications)
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, t
