Novel high-throughput fluorescence-based assay for the identification of nematocidal compounds that target the blood-feeding pathway (Publications)
Hookworm infections cause a neglected tropical disease (NTD) affecting ~740 million people worldwide, principally those living in disadvantaged communities. Infections can cause high morbidity due to
Long-term exposure to source-specific fine particles and mortality horizontal line a pooled analysis of 14 European cohorts within the ELAPSE project (Publications)
We assessed mortality risks associated with source-specific fine particles (PM2.5) in a pooled European cohort of 323,782 participants. Cox proportional hazard models were applied to estimate mortalit
Using open-access data to explore relations between urban landscapes and diarrhoeal diseases in Côte d'Ivoire (Publications)
Unlike water and sanitation infrastructures or socio-economic indicators, landscape features are seldomly considered as predictors of diarrhoea. In contexts of rapid urbanisation and changes in the ph
Effects of structurally different HDAC inhibitors against <em>Trypanosoma cruzi</em>, <em>Leishmania</em>, and <em>Schistosoma mansoni</em> (Publications)
Neglected tropical diseases (NTDs), including trypanosomiasis, leishmaniasis, and schistosomiasis, result in a significant burden in terms of morbidity and mortality worldwide every year. Current anti
Industrial mining and HIV risk: evidence from 39 mine openings across 16 countries in sub-Saharan Africa (Publications)
OBJECTIVES: The aim of this study was to assess the impact of natural resource extraction projects on HIV transmission risks in local communities in sub-Saharan Africa. DESIGN: Difference-in-differenc
Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral... (Publications)
INTRODUCTION: HIV programmes across many countries in Africa have recently transitioned people living with HIV from efavirenz (EFV)- to dolutegravir (DTG)-containing antiretroviral therapy (ART). As b
Treatment outcome of imported cutaneous leishmaniasis among travellers and migrants infected with<em> Leishmania major</em> and <em>Leishmania... (Publications)
OBJECTIVES: Cutaneous leishmaniasis (CL) in Asia, Northern and Sub-Saharan Africa is mainly caused by Leishmania major and Leishmania tropica. We describe and evaluate the treatment outcome of CL amon
Parasite viability as a measure of <em>in vivo</em> drug activity in preclinical and early clinical antimalarial drug assessment (Publications)
The rate at which parasitemia declines in a host after treatment with an antimalarial drug is a major metric for assessment of antimalarial drug activity in preclinical models and in early clinical tr
Priority setting in early childhood development: an analytical framework for economic evaluation of interventions (Publications)
BACKGROUND: Early childhood development (ECD) sets the foundation for healthy and successful lives with important ramifications for education, labour market outcomes and other domains of well-being. E