<em>In vitro </em>drug efficacy testing against <em>Trypanosoma brucei</em> (Publications)
The recent endorsement of fexinidazole by the European Medicines Agency for the treatment of human African trypanosomiasis has demonstrated the high predictive value of cell-based assays for parasite
Model-based integration of genomics and metabolomics reveals SNP functionality in <em>Mycobacterium tuberculosis</em> (Publications)
Human tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) that vary in virulence and transmissibility. While genome-wide association studies have uncovered several mutat
The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development (Publications)
AIMS: Imbalances of iron metabolism have been linked to the development of atherosclerosis. However, subjects with hereditary haemochromatosis have a lower prevalence of cardiovascular disease. The ai
Ultradian modulation of cortical arousals during sleep: effects of age and exposure to nighttime transportation noise (Publications)
STUDY OBJECTIVES: The present study aimed at assessing the temporal non-rapid eye movement (NREM) EEG arousal distribution within and across sleep cycles and its modifications with aging and nighttime
Concurrently measured concentrations of atmospheric mercury in indoor (household) and outdoor air of Basel, Switzerland (Publications)
Indoor air pollution can be a major health risk because urban populations spend up to 90% of their time in closed rooms. Gaseous elemental mercury (GEM) has not been measured as routinely as other ind
Aging does not impact drug-drug interaction magnitudes with antiretrovirals: a Swiss HIV Cohort Study (Publications)
The risk of drug-drug interactions (DDIs) is elevated in aging people living with HIV (PLWH) due to highly prevalent age-related comorbidities leading to more comedications. To investigate the impact
Physical discipline, deprivation, and differential risk of developmental delay across 17 countries (Publications)
OBJECTIVE: Parenting behaviors have largely been studied in isolation with regard to child development in cross-national contexts. We examine and compare the relative strength of association between p
Short communication on the use of a free rabies hotline service in Chad (Publications)
As part of the activities of a project to estimate burden of rabies and vaccine demand in Chad, funded by GAVI, we set up a free hotline service to guide the population and related public services in
Estimation of dog population and dog bite risk factors in departments of San Pedro and Bouake in Côte d'Ivoire (Publications)
Rabies is endemic in Cote d'Ivoire and was identified in January 2017 as a priority zoonosis by all stakeholders in public health. A well-designed integrated national rabies control is essential to at