Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline... (Publications)
BACKGROUND: Patients with borderline resectable pancreatic ductal adenocarcinoma have relatively low resection rates and poor survival despite the use of adjuvant chemotherapy. The aim of our study wa
The burden of surgical site infections and related antibiotic resistance in two geographic regions of Sierra Leone: a prospective study (Publications)
Despite the prolongation of hospitalization, increase in morbidity, mortality and cost of care associated with both surgical site infections (SSIs) and antibiotic resistance, there are limited data on
Long-term air pollution exposure and Parkinson's disease mortality in a large pooled European cohort: an ELAPSE study (Publications)
BACKGROUND: The link between exposure to ambient air pollution and mortality from cardiorespiratory diseases is well established, while evidence on neurodegenerative disorders including Parkinson's Di
Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against <em>Haemophilus... (Publications)
Defense against Haemophilus influenzae type b (Hib) is dependent on antibodies and complement, which mediate both serum bactericidal activity (SBA) and opsonophagocytosis. Here we evaluated the influe
The need to address fragmentation and silos in mortality information systems: the case of Ghana and Peru (Publications)
Objectives: We aimed to understand the information architecture and degree of integration of mortality surveillance systems in Ghana and Peru. Methods: We conducted a cross-sectional study using a com
Epidemiology of pediatric schistosomiasis in hard-to-reach areas and populations: a scoping review protocol (Publications)
Background: Schistosomiasis is a neglected tropical disease (NTD) that affects millions of people. Children are the most vulnerable group to developing overt disease. An estimated 779 million people a
Fast-killing tyrosine amide ((<em>S</em>)-SW228703) with blood- and liver-stage antimalarial activity associated with the cyclic amine resistance... (Publications)
Current malaria treatments are threatened by drug resistance, and new drugs are urgently needed. In a phenotypic screen for new antimalarials, we identified (S)-SW228703 ((S)-SW703), a tyrosine amide
Introducing the Library of Guidance for Health Scientists (LIGHTS): a living database for methods guidance (Publications)
IMPORTANCE: Improving methodological quality is a priority in the health research community. Finding appropriate methods guidance can be challenging due to heterogeneous terminology, poor indexing in
Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU... (Publications)
As one of the core elements of the European Human Biomonitoring Initiative (HBM4EU) a human biomonitoring (HBM) survey was conducted in 23 countries to generate EU-wide comparable HBM data. This surve
Effectiveness of a peer educator-coordinated preference-based differentiated service delivery model on viral suppression among young people living... (Publications)
BACKGROUND: Southern and Eastern Africa is home to more than 2.1 million young people aged 15 to 24 years living with HIV. As compared with other age groups, this population group has poorer outcomes