Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from <em>Photorhabdus laumondii</em> (Publications)
The glidobactin-like natural products (GLNPs) glidobactin A and cepafungin I have been reported to be potent proteasome inhibitors and are regarded as promising candidates for anti-cancer drug develop
Unusual derivatives from <em>Hypericum scabrum</em> (Publications)
Three new compounds (1-3) with unusual skeletons were isolated from the n-hexane extract of the air-dried aerial parts of Hypericum scabrum. Compound 1 represents the first example of an esterified po
Impact of social accountability monitoring on health facility performance: evidence from Tanzania (Publications)
Social accountability programs are increasingly used to improve the performance of public service providers in low-income settings. Despite their growing popularity, evidence on the effectiveness of s
Enhancing the understanding of resilience in health systems of low- and middle-income countries: a qualitative evidence synthesis (Publications)
Background A country’s health system faces pressure when hit by an unexpected shock, such as what we observe in the midst of the coronavirus disease 2019 (COVID-19) pandemic. The concept of resilience
Structure of trypanosome coat protein VSGsur and function in suramin resistance (Publications)
Suramin has been a primary early-stage treatment for African trypanosomiasis for nearly 100 yr. Recent studies revealed that trypanosome strains that express the variant surface glycoprotein (VSG) VSG
Young people's experiences using an on-demand mobile health sexual and reproductive health text message intervention in Kenya: qualitative study (Publications)
BACKGROUND: Digital health usability assessments can help explain how well mobile health (mHealth) apps targeting young people with sexual and reproductive health (SRH) information performed and wheth
Pharyngeal carriage of beta-haemolytic <em>Streptococcus </em>species and seroprevalence of anti-streptococcal antibodies in children in Bouaké, Côte... (Publications)
The pharynx of the child may serve as a reservoir of pathogenic bacteria, including beta-haemolytic group A streptococci (GAS), which can give rise to upper airway infections and post-streptococcal di
A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials (Publications)
OBJECTIVES: To systematically assess the kind of placebos used in investigator-initiated randomized controlled trials (RCTs), where they are obtained, and what hurdles exist in obtaining them. STUDY D
Development of Europe-wide models for particle elemental composition using supervised linear regression and random forest (Publications)
We developed Europe-wide models of long-term exposure to eight elements (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in particulate matter with diameter
