Multiplexed ddPCR-amplicon sequencing reveals isolated <em>Plasmodium falciparum</em> populations amenable to local elimination in Zanzibar, Tanzania (Publications)
Zanzibar has made significant progress toward malaria elimination, but recent stagnation requires novel approaches. We developed a highly multiplexed droplet digital PCR (ddPCR)-based amplicon sequenc
Factors associated with COVID-19 non-vaccination in Switzerland: a nationwide study (Publications)
Objectives: We compared socio-demographic characteristics, health-related variables, vaccination-related beliefs and attitudes, vaccination acceptance, and personality traits of individuals who vaccin
From contigs towards chromosomes: automatic improvement of long read assemblies (ILRA) (Publications)
Recent advances in long read technologies not only enable large consortia to aim to sequence all eukaryotes on Earth, but they also allow individual laboratories to sequence their species of interest
Plasma concentrations of per- and polyfluoroalkyl substances in pregnancy and breastfeeding duration in Project Viva (Publications)
BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) may disrupt mammary gland development and function; thereby inhibiting milk supply and breastfeeding duration. However, conclusions on the potent
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections (Publications)
Millions who live in Latin America and sub-Saharan Africa are at risk of trypanosomatid infections, which cause Chagas disease and human African trypanosomiasis (HAT). Improved HAT treatments are avai
Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant <em>Mycobacterium tuberculosis </em>in Cape Town, South... (Publications)
BACKGROUND: Experimental data show that drug-resistance-conferring mutations are often associated with a decrease in the replicative fitness of bacteria in vitro, and that this fitness cost can be mit
Association of long-term exposure to ambient air pollution with retinal neurodegeneration: the prospective Alienor study (Publications)
Chronic exposure to air pollution may have adverse effects on neurodegenerative diseases. Glaucoma, the second leading cause of blindness worldwide, is a neurodegenerative disease of the optic nerve,
Intestinal helminth infections and associated risk factors among adults in the Lao People's Democratic Republic (Publications)
BACKGROUND: Helminthiases are highly endemic in Southeast Asia, including the Lao People's Democratic Republic (Lao PDR). This study aimed to assess the current intestinal helminth infections and the
Impacts of weather and air pollution on Legionnaires' disease in Switzerland: a national case-crossover study (Publications)
BACKGROUND: The number of reported cases of Legionnaires' disease (LD) has risen markedly in Switzerland (6.5/100,000 inhabitants in 2021) and abroad over the last decade. Legionella, the causative ag