The <em>Plasmodium </em>lactate/H+ transporter PfFNT is essential and druggable <em>in vivo</em> (Publications)
Malaria parasites in the blood stage express a single transmembrane transport protein for the release of the glycolytic end product l-lactate/H(+) from the cell. This transporter is a member of the st
Investigation of sources of fluorinated compounds in private water supplies in an oil and gas-producing region of Northern West Virginia (Publications)
Per- and polyfluoroalkyl substances (PFASs) are a class of toxic organic compounds that have been widely used in consumer applications and industrial activities, including oil and gas production. We m
A new global air quality health index based on the WHO Air Quality Guideline values with application in Cape Town (Publications)
Objectives: This study developed an Air Quality Health Index (AQHI) based on global scientific evidence and applied it to data from Cape Town, South Africa. Methods: Effect estimates from two global s
Efficacy and safety of moxidectin compared with ivermectin against <em>Strongyloides stercoralis</em> infection in adults in Laos and Cambodia: a... (Publications)
BACKGROUND: Infection with the soil-transmitted helminth Strongyloides stercoralis affects up to 600 million people globally, most of whom live in rural areas with poor sanitation. If untreated, infec
<em>Trypanosoma cruzi</em> STIB980: a TcI strain for drug discovery and reverse genetics (Publications)
Since the first published genome sequence of Trypanosoma cruzi in 2005, there have been tremendous technological advances in genomics, reverse genetics, and assay development for this elusive pathogen
Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global... (Publications)
BACKGROUND: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical frame
COVID-19 screening in low resource settings using artificial intelligence for chest radiographs and point-of-care blood tests (Publications)
Artificial intelligence (AI) systems for detection of COVID-19 using chest X-Ray (CXR) imaging and point-of-care blood tests were applied to data from four low resource African settings. The performan
Care cascades for hypertension in low-income settings: a systematic review and meta-analysis (Publications)
Objective: High blood pressure is the leading risk factor for cardiovascular disease. The hypertension care cascade (HCC) is increasingly being used to evaluate the effectiveness of interventions. Thi
