Aircraft noise exposure and risk for recurrent cardiovascular events after acute coronary syndrome: a prospective patient cohort study (Publications)
In several population based cohort studies associations between aircraft noise and various diagnoses of cardiovascular disease were observed. However, no study has yet addressed the risk of recurrence
Antimalarial dibenzannulated medium-ring keto lactams (Publications)
We discovered dibenzannulated medium-ring keto lactams (11,12-dihydro-5H-dibenzo[b,g]azonine-6,13-diones) as a new antimalarial chemotype. Most of these had chromatographic LogD(7.4) values ranging fr
The footprint of human-induced climate change on heat-related deaths in the summer of 2022 in Switzerland (Publications)
Human-induced climate change is leading to an increase in the intensity and frequency of extreme weather events, which are severely affecting the health of the population. The exceptional heat during
Effects of adjuvant berberine therapy on acute ischemic stroke: a meta-analysis (Publications)
We conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications
Multisystemic resilience to shocks: a temporal analysis of health, fundamental rights and freedoms, and economic resilience during the first wave of... (Publications)
OBJECTIVES: Research on resilience to the COVID-19 pandemic has primarily focused on health system resilience. The purpose of this paper is to: (1) develop a broader understanding of societal resilien
Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria (Publications)
Individual-based models have become important tools in the global battle against infectious diseases, yet model complexity can make calibration to biological and epidemiological data challenging. We p
Lived experiences and perceptions of childbirth among pastoralist women in north-eastern Ethiopia: a multimethod qualitative analysis to the WHO... (Publications)
Maternity should be a time of hope and joy. However, for women in pastoralist communities in Ethiopia, the reality of motherhood is often grim. This problem is creating striking disparities of skilled
Economic evaluation of disease elimination: an extension to the net-benefit framework and application to human African trypanosomiasis (Publications)
The global health community has earmarked a number of diseases for elimination or eradication, and these goals have often been praised on the premise of long-run cost savings. However, decision makers
Optimizing moxidectin dosing for <em>Strongyloides stercoralis</em> infections: insights from pharmacometric modeling (Publications)
Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile