Randomised trial of SPf66 vaccine against <em>Plasmodium falciparum</em> malaria in children in southern Tanzania (Publications)
Malaria, especially that due to Plasmodium falciparum, is one of the most important parasitic disease in man. It causes more than 400 million cases per year and between 1 to 3 million deaths, mainly a
Parallel synthesis and antileishmanial activity of ether-linked phospholipids (Publications)
The synthesis and antileishmanial activity of 18 edelfosine analogues are described. Compounds were obtained in parallel combining solid phase and solution phase synthesis. The most active analogue is
Use of spoligotyping and large sequence polymorphisms to study the population structure of the <em>Mycobacterium tuberculosis</em> complex in a cohort... (Publications)
Mycobacterium africanum, first described in Senegal in 1968, causes up to half of the smear-positive pulmonary tuberculosis cases in West Africa, but it has not been found in other geographical areas
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
