Variable host-pathogen compatibility in <em>Mycobacterium tuberculosis</em> (Publications)
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide. Studies have reported human pathogens to have geographically structured population genetics, some of which have b
The competitive cost of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Mathematical models predict that the future of the multidrug-resistant tuberculosis epidemic will depend on the fitness cost of drug resistance. We show that in laboratory-derived mutants of Mycobacte
Global phylogeography of <em>Mycobacterium tuberculosis</em> and implications for tuberculosis product development (Publications)
New tools for controlling tuberculosis are urgently needed. Despite our emerging understanding of the biogeography of Mycobacterium tuberculosis, the implications for development of new diagnostics, d
Fitness cost of drug resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Multidrug-resistant (MDR)--and extensively drug-resistant (XDR)--forms of tuberculosis are growing public health problems. Mathematical models predict that the future of the MDR and XDR tuberculosis e