New <em>in vitro</em> interaction-parasite reduction ratio assay for early derisk in clinical development of antimalarial combinations (Publications)
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but requ
Effects of contact with a dog on prefrontal brain activity: a controlled trial (Publications)
BACKGROUND: There is a broad range of known effects of animal contact on human mental and physical health. Neurological correlates of human interaction with animals have been sparsely investigated. We
Does global health governance walk the talk? Gender representation in World Health Assemblies, 1948-2021 (Publications)
BACKGROUND: While an estimated 70%-75% of the health workforce are women, this is not reflected in the leadership roles of most health organisations-including global decision-making bodies such as the
Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT) (Publications)
Human African Trypanosomiasis (HAT) is a vector-borne disease caused by kinetoplastid parasites of the Trypanosoma genus. The disease proceeds in two stages, with a hemolymphatic blood stage and a men
Deconstructing design thinking as a tool for the implementation of a population health initiative (Publications)
BACKGROUND: The translation of evidence-based practices and rapid uptake of innovations into global health practice is challenging. Design thinking is a consultative process involving multiple stakeho
Different classes of genomic inserts contribute to human antibody diversity (Publications)
Recombination of antibody genes in B cells can involve distant genomic loci and contribute a foreign antigen-binding element to form hybrid antibodies with broad reactivity for Plasmodium falciparum.
2-(Nitroaryl)-5-substituted-1,3,4-thiadiazole derivatives with antiprotozoal activities: <em>in vitro</em> and <em>in vivo </em>study (Publications)
Nitro-containing compounds are a well-known class of anti-infective agents, especially in the field of anti-parasitic drug discovery. HAT or sleeping sickness is a neglected tropical disease caused by
Europe-wide air pollution modeling from 2000 to 2019 using geographically weighted regression (Publications)
Previous European land-use regression (LUR) models assumed fixed linear relationships between air pollution concentrations and predictors such as traffic and land use. We evaluated whether including s
Phenotypic screening of histone deacetylase (HDAC) inhibitors against <em>Schistosoma mansoni</em> (Publications)
Schistosomiasis is a prevalent yet neglected tropical parasitic disease caused by the Schistosoma genus of blood flukes. Praziquantel is the only currently available treatment, hence drug resistance p
