Diarrhoea among children aged under five years and risk factors in informal settlements: a cross-sectional study in Cape Town, South Africa (Publications)
Background: There is limited data on the association between diarrhoea among children aged under five years (U5D) and water use, sanitation, hygiene, and socio-economics factors in low-income communit
Association of livestock ownership and household dietary quality: results from a cross-sectional survey from rural India (Publications)
Studies from India and several eastern African countries found that the impact of dairy animal ownership on household nutrition varied greatly, depending on the socio-geographic context. The purpose o
Fostering cardiovascular health at work - case study from Senegal (Publications)
BACKGROUND: Of the 15 million annual premature deaths from non-communicable diseases (NCDs), 85% occur in low- and middle-income countries (LMICs). Affecting individuals in the prime of their lives, N
Efficacy and tolerability of quinacrine monotherapy and albendazole plus chloroquine combination therapy in nitroimidazole-refractory giardiasis: a... (Publications)
BACKGROUND: Giardiasis failing nitroimidazole first-line treatment is an emerging problem in returning European travelers. We present data on the efficacy and tolerability of 2 second-line treatment r
Urogenital schistosomiasis infection prevalence targets to determine elimination as a public health problem based on microhematuria prevalence in... (Publications)
BACKGROUND: Recent research suggests that schistosomiasis targets for morbidity control and elimination as a public health problem could benefit from a reanalysis. These analyses would define evidence
Cost of illness for severe and non-severe diarrhea borne by households in a low-income urban community of Bangladesh: a cross-sectional study (Publications)
The illness cost borne by households, known as out-of-pocket expenditure, was 74% of the total health expenditure in Bangladesh in 2017. Calculating economic burden of diarrhea of low-income urban com
Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a... (Publications)
BACKGROUND: Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans; however, the current tablet formulation is not su
Characterization of moxidectin against <em>Strongyloides ratti:</em> <em>in vitro</em> and<em> in vivo </em>activity and pharmacokinetics in the rat... (Publications)
Strongyloides stercoralis is a soil-transmitted helminth affecting an estimated 30-100 million people. Since the infection may be severe and life-threatening, accessible and effective treatment is piv
Spatial epidemiology of urban health risks in select West African cities (Publications)
West African cities face critical societal challenges that are linked to environmental and health changes. These challenges are further exacerbated by urbanization dynamics, climate change, socio-econ
Cytochrome P450-mediated metabolism and CYP Inhibition for the synthetic peroxide antimalarial OZ439 (Publications)
OZ439 is a potent synthetic ozonide evaluated for the treatment of uncomplicated malaria. The metabolite profile of OZ439 was characterized in vitro using human liver microsomes combined with LC/MS-MS