Antimalarial benzimidazole derivatives incorporating phenolic mannich base side chains inhibit microtubule and hemozoin formation: structure-activity... (Publications)
A novel series of antimalarial benzimidazole derivatives incorporating phenolic Mannich base side chains at the C2 position, which possess dual asexual blood and sexual stage activities, is presented.
From "learning from the field" to jointly driving change (Publications)
The theme of the 8th edition of the Geneva Health Forum (GHF) was Improving access to health: learning from the field. While 'the field' often denotes people, patients, communities, and healthcare wor
Antimicrobial resistance in humans, animals, water and household environs in rural Andean Peru: exploring dissemination pathways through the One... (Publications)
Antimicrobial resistance (AMR) is a global public health threat, especially for low and middle-income countries (LMIC) where the threat has not been fully identified. Our study aims to describe E. col
Effectiveness of animal-assisted interventions for children and adults with post-traumatic stress disorder symptoms: a systematic review and... (Publications)
Background: Animal-assisted interventions (AAI) are increasingly applied for people with post-traumatic stress disorder (PTSD) symptoms albeit its effectiveness is unclear. Objectives: To examine the
How are academic achievement and inhibitory control associated with physical fitness, soil-transmitted helminth infections, food insecurity and... (Publications)
BACKGROUND: Cardiovascular fitness has been associated with both executive function and academic achievement in multiple cohort studies including children and adolescents. However, research is scarce
New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities (Publications)
An N-acylated furazan-3-amine of a Medicines for Malaria Venture (MMV) project has shown activity against different strains of Plasmodium falciparum. Seventeen new derivatives were prepared and tested
Multiple air pollutant exposure and lung cancer in Tehran, Iran (Publications)
Lung cancer is the most rapidly increasing malignancy worldwide with an estimated 2.1 million cancer cases in the latest, 2018 World Health Organization (WHO) report. The objective of this study was t
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting <em>Plasmodium falciparum</em> (Publications)
3-Hydroxypropanamidines are a new promising class of highly active antiplasmodial agents. The most active compound 22 exhibited excellent antiplasmodial in vitro activity with nanomolar inhibition of
