Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 (Publications)
Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibi
Gut microbiota targeted approach in the management of chronic liver diseases (Publications)
The liver is directly connected to the intestines through the portal vein, which enables the gut microbiota and gut-derived products to influence liver health. There is accumulating evidence of decrea
Together yet apart: remedies for tensions between volunteers and health care professionals in inter-professional collaboration (Publications)
While volunteering is an essential factor in service delivery in many societal areas, the inclusion of volunteers in formal settings can also lead to tensions. In this article, we combine the literatu
Inequality in the quality of health services: wealth, content of care, and the price of antenatal consultations in the Democratic Republic of Congo (Publications)
We use unique data on direct observations of patient-provider interactions linked to detailed patient exit interviews and household surveys to study the relationship between patients’ socioeconomic st
Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection (Publications)
The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,13
CD38 expression by antigen-specific CD4 t cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load... (Publications)
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, t
Der lange Weg zur ersten Impfung gegen Malaria (Publications)
Ein historisches Ereignis nach einem langen Weg: Die Weltgesundheitsorganisation hat jüngst den Einsatz des ersten Impfstoffes gegen Malaria zum breitflächigen Einsatz bei Kindern in den betroffenen
Le long chemin vers le premier vaccin antipaludique (Publications)
Un événement historique après un long chemin: l’Organisation mondiale de la santé a récemment recommandé l’utilisation à grande échelle du premier vaccin antipaludique chez les enfants des pays concer
Framework synthesis to inform the ideation and design of a paper-based health information system (PHISICC) (Publications)
BACKGROUND: Health information systems (HIS) are meant to support decision-making at all levels of the system, including frontline health workers. In field studies in Cote d'Ivoire, Mozambique and Nig