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1. Reduced exposure to PM10 and attenuated age-related decline in lung function (Publications)

   Reduced exposure to PM10 and attenuated age-related decline in lung function

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   BACKGROUND: Air pollution has been associated with impaired health, including reduced lung function in adults. Moving to cleaner areas has been shown to attenuate adverse effects of air pollution on l

2. Early menarche and new onset of asthma: results from the SAPALDIA cohort study (Publications)

   Early menarche and new onset of asthma: results from the SAPALDIA cohort study

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3. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)

   1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

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   HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re

4. Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project (Publications)

   Natural cause mortailty and long-term exposure to particle components: an analysis of 19 european cohorts within the multi-center ESCAPE project

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5. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies (Publications)

   Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

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   BACKGROUND: Epigenetic variations in peripheral blood have potential as biomarkers for disease. This systematic review assesses the association of lung function and chronic obstructive pulmonary disea

6. Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)

   Infectious diseases are associated with carotid intima media thickness in adolescence

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   OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious

7. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Publications)

   Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

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   Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals

8. Land use regression models for ultrafine particles in six European areas (Publications)

   Land use regression models for ultrafine particles in six European areas

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   Long-term ultrafine particle (UFP) exposure estimates at a fine spatial scale are needed for epidemiological studies. Land use regression (LUR) models were developed and evaluated for six European are

9. The adverse impact of obesity on heart rate variability is modified by a <em>NFE2L2 </em>gene variant: the SAPALDIA Cohort (Publications)

   The adverse impact of obesity on heart rate variability is modified by a <em>NFE2L2 </em>gene variant: the SAPALDIA Cohort

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   BACKGROUND: Overweight has been associated with an increase in inflammatory markers and with an imbalance in the autonomic nervous system, such as a decrease in heart rate variability (HRV). In this s

10. Associations between domains of physical activity, sitting time, and different measures of overweight and obesity (Publications)

    Associations between domains of physical activity, sitting time, and different measures of overweight and obesity

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